BDBM25191 4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-yl}-1,3-thiazole-2-carbaldehyde::7-substituted 4-anilinoquinoline, 31::BMCL174363 Compound 1::BMCL18318 Compound 1

SMILES Cc1ccc(O)cc1Nc1ccnc2cc(ccc12)-c1csc(C=O)n1

InChI Key InChIKey=VKQPTVJDZIILPG-UHFFFAOYSA-N

Data  3 KI  5 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 25191   

TargetProto-oncogene tyrosine-protein kinase receptor Ret(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM25191(4-{4-[(5-hydroxy-2-methylphenyl)amino]quinolin-7-y...)
Affinity DataIC50:  25nMpH: 7.4 T: 2°CAssay Description:The biochemical activity of compound was determined by incubation with Ret kinase and the substrate in the presence of ATP/ [gamma-33P] ATP. After in...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed